Alcohols and polyols
- (1)
- (55)
- (354)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (31)
- (14)
- (3)
- (1)
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- (10)
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- (30)
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- (20)
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- (5)
- (400)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (14)
- (148)
- (116)
- (9)
- (5)
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- (30)
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- (20)
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- (1)
- (4)
- (6)
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- (3)
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- (29)
- (7)
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- (1)
- (36)
- (5)
- (4)
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- (5)
- (4)
- (17)
- (15)
- (4)
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- (1)
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- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (13)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (4)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
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- (1)
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- (9)
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- (12)
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- (1)
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- (10)
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- (1)
- (1)
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- (11)
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- (1)
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Medchemexpress LLC Ladostigil hydrochlo 5mg | 209394-18-3 | 5MG
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Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with IC50s of 37 1 and 31 8 M for MAO-B and AChE respectively Ladostigil hydrochloride exhibits neuroprotective antioxidant and anti-inflammatory activities Ladostigil can be used for the research of depression and Alzheimer s disease[1 [2 Ladostigil (hydrochloride) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Medchemexpress LLC Amprolium (hydrochloride) | 137-88-2 | 98.8% | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amprolium hydrochloride is an anti-parasitic drug that is taken orally and acts as an antagonist to thiamine in intestinal absorption. With a molecular formula of C14H20Cl2N4 and a molecular weight of 315.24, this compound is supplied as a white to off-white solid with a high purity of 98.79%.
- Anti-parasitic drug targeting coccidia
- Acts as a thiamine antagonist
- High purity of 98.79%
- White to off-white solid appearance
- Soluble in water (≥ 200 mg/mL)
- Recommended storage at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Alectinib (Hydrochloride) | 1256589-74-8 | 99.9% | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Alectinib Hydrochloride is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It effectively inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively, and demonstrates effective central nervous system (CNS) penetration.
- Potent, selective, and orally available ALK inhibitor
- Effective central nervous system (CNS) penetration
- Molecular formula: C30H35ClN4O2
- Molecular weight: 519.08
- Appearance: White to off-white solid
- Recommended storage at 4°C, sealed and away from moisture
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Medchemexpress LLC SB-277011 (hydrochloride) | 215804-67-4 | 99.6% | 475.02 | 25 MG
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SB-277011 hydrochloride is a potent, selective, orally bioavailable, and brain-penetrant dopamine D3 receptor (D3R) antagonist. It demonstrates 80- to 100-fold selectivity over other dopamine receptors.
- Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively.
- Selectivity over D2, 5-HT1B, and 5-HT1D receptors.
- Oral bioavailability of 43% and a half-life of 2.0 h in rats.
- High brain-penetrant (brain:blood ratio of 3.6:1).
- Reverses quinelorane effects in the nucleus accumbens at 3 mg/kg (p.o.) in rats.
- Reduces intravenous cocaine self-administration in rats (12.5-25 mg/kg, i.p.).
- Inhibits basal and cocaine-enhanced locomotion in rats at 50 mg/kg.
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Medchemexpress LLC Pumosetrag hydrochloride | 194093-42-0 | 99.77% | 339.84 | 100 MG
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Pumosetrag hydrochloride | 194093-42-0 | 99.77% | 339.84 | 100 MG
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Medchemexpress LLC SCH-23390 (hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 100 MG
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SCH-23390 (hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 100 MG
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Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 100.0% | 362.30 | 50 MG
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Clemizole hydrochloride is an H1 histamine receptor antagonist that has been shown to substantially inhibit HCV replication. It also acts as an inhibitor of the TRPC5 channel. The IC50 of Clemizole hydrochloride for RNA binding by NS4B is 24 nM, while its EC50 for viral replication is 8 μM.
- Inhibits HCV RNA replication in cell culture.
- Suppresses NS4B's RNA binding.
- Offers minimal host cell toxicity.
- Functions as a novel inhibitor of TRPC5 channels.
- Efficiently blocks TRPC5 currents and Ca2+ entry in the low micromolar range.
- Exhibits six-fold selectivity for TRPC5 over TRPC4β.
- Displays almost 10-fold selectivity over TRPC3 and TRPC6.
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Medchemexpress LLC PhiKan 083 hydrochlo | 1050480-30-2 | 99.3% | 274.79 | 10 MG
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PhiKan 083 hydrochloride is a carbazole derivative that functions as a p53 Y220C stabilizer. It binds to the surface cavity of the Y220C (a p53 mutant) with a Kd of 167 μM and demonstrates a relative binding affinity (Kd) of 150 μM in Ln229 cells. This compound has been shown to slow down the thermal denaturation rate of p53 Y220C.
- Binds to the surface cavity of p53 Y220C mutant.
- Stabilizes p53 Y220C.
- Exhibits a Kd of 167 μM for p53 Y220C.
- Shows a relative binding affinity of 150 μM in Ln229 cells.
- Slows the thermal denaturation rate.
- Reduces cell viability of engineered Ln229 cell variants.
- Enhances pro-apoptotic activity in Ln229 cells when combined with NSC 123127.
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Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.1% | 321.93 | 25 MG
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Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells. Its activity is not affected by androgen receptor status, and it suppresses the transcriptional activity of the androgen receptor.
- Tricyclic diterpene molecule
- Extracted from the bark of pine trees
- Cannabinoid receptor type 1 (CB1) agonist
- Inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
- Suppresses transcriptional activity of androgen receptor
- Appearance: solid
- Color: white to off-white
- For research use only
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Medchemexpress LLC NNMT-IN-6 hydrochloride | 3031756-18-7 | 98.2% | C25H30ClN7O5 | 10MG
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NNMT-IN-6 hydrochloride is the hydrochloride salt of a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) intended for research use. It exhibits in vitro inhibitory activity (IC50 = 1.41 μM; Kd = 5.6 μM) and is supplied as a high-purity solid with documented solubility and storage recommendations for biochemical and cellular assays.
- High purity (98.2%).
- Confirmed NNMT inhibitory activity (IC50 = 1.41 μM; Kd = 5.6 μM).
- Hydrochloride salt form for improved solubility.
- Validated solubility in DMSO and water (250 mg/mL with sonication).
- Suitable for biochemical and cellular assays targeting NNMT.
- Recommended sealed storage away from moisture, with solvent stability guidelines.
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Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 5 G
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Trazodone hydrochloride is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is suitable for various laboratory applications and research.
- Exhibits anti-depressant and anti-insomnious activity
- Acts as an antagonist against α1- and α2-adrenergic receptors
- Antagonizes histamine H1 receptors
- Demonstrates minimal anticholinergic effects
- Binds to 5-HT1A receptor
- Reduces expression of neuroinflammatory markers
- Increases mRNA expression of BDNF and CREB
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Medchemexpress LLC Pholedrine (hydrochloride) | 877-86-1 | 99.6% | 100 MG
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Pholedrine (hydrochloride) is an indirectly acting sympathomimetic amine supplied as a solid hydrochloride salt for laboratory research and substance manufacture. It has a reported molecular formula C10H16ClNO and a molecular weight of 201.69 g/mol.
- CAS 877-86-1
- Molecular formula C10H16ClNO
- Molecular weight 201.69 g/mol
- Appearance solid
- Recommended storage 4°C, sealed, away from moisture
- Purity 99.6% (LCMS)
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Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 50MG
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Viloxazine hydrochloride is a research-grade small molecule used as a selective norepinephrine transporter (NET) inhibitor and a modulator of serotonin (5-HT) receptors. Presented as the hydrochloride salt (CAS 35604-67-2) and supplied for preclinical laboratory use, it is commonly employed as a tool compound in studies of norepinephrine and serotonin signaling and in ADHD-related research.
- Research-grade hydrochloride salt with defined purity for laboratory use.
- Selective norepinephrine transporter inhibitor activity (IC50 = 0.26 μM).
- Modulates 5-HT receptors, including 5-HT2B antagonist and 5-HT2C agonist actions.
- Available in small pack sizes suitable for assays, including a 50 mg pack.
- Provided with molecular and analytical data to support traceability and reproducibility.
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Medchemexpress LLC Abeprazan hydrochloride | 1902954-87-3 | 99.9% | 446.87 | 50 MG
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Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker that inhibits H+, K+- ATPase through reversible potassium-competitive ionic binding without requiring acid activation. It is being developed as a potential alternative to proton pump inhibitors for treating acid-related diseases.
- Potassium-competitive acid blocker.
- Inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding.
- Does not require acid activation for its inhibitory mechanism.
- Developed as a potential alternative for proton pump inhibitors.
- Inhibits acid secretion in a dose-dependent manner in in vivo studies.
- Efficacy is equal to or greater than that of vonoprazan in various in vivo studies.
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Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | MFCD01319147 | 99.9% | 390.93 | C17H27ClN2O4S | 10 MG
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Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 receptor antagonist supplied as a white to off-white solid for laboratory research applications. It is provided at high reported purity and in small pack sizes for bench-top experiments.
- Selective dopamine D2 receptor antagonist.
- High purity (≈99.9%).
- White to off-white solid physical form.
- CAS number 23694-17-9.
- Molecular weight 390.93 g/mol.
- Available in small pack sizes, including 10 MG.
- Intended for research use only; not for human or clinical use.
- Storage: 4°C, sealed and away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.
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